Shopping Cart

Your cart is empty

Continue Shopping

Scientific Supplement Core Duo


Made in collaboration with Dr Steven Gabriel, PhD, Expert in Regenerative Medicine and Anti-ageing, Gerontologist, long time fan of One Truth 818.

SCIENTIFIC SUPPLEMENTS are the perfect partner to our popular Scientific Skincare range because beauty is not only skin deep, anti-ageing must come from the inside too.

REPAIR helps keep your mind and body young. It uses all natural ingredients that work together to activate telomerase to help lengthen your telomeres, as well as the key natural ingredients that protect your telomeres from shortening.

ELIMINATE works in synchronicity with REPAIR. While we are keeping your telomeres as long as possible-there will be cells that develop critically short telomeres. Those cells can wreak havoc on neighboring cells and age your entire body. These dangerous cells create the “waterfall effect” of aging. It’s important that we do everything we can to turn those cells off or eliminate them. ELIMINATE is designed to eliminate or shut off those cells that age your mind and body.

Telomere Support 4x 500mg capsules contain:
Curcumin 1000mg, L Carnosine 500mg, Silybin 200mg, Glutathione 100mg, Astragalus 80mg, Black pepper extract 8mg, Vitamin D (10,000i.u) Also contains magnesium stearate, hypromellose and natural colouring, Vegan. Free from gluten and dairy.

Senolytic Therapy 3 x 500mg capsules contain:
Quercetin 525mg, Epigallocatechin gallate (green tea extract) 525mg, Pterostilbene 300mg, Zinc 60mg, Black pepper extract 6mg, Also contains magnesium stearate, hypromellose and natural colouring. Vegan. Free from gluten and dairy.

It has long been known that keeping telomeres long is the key to youth.  The longer your telomeres, the younger you are biologically.  Almost every disease known to humankind has been linked to critically short telomeres.  Lucky for us there are proven, natural ingredients that can re-lengthen your telomere and others that can slow down the rate of shortening.  A combination of these proven ingredients is used in our 'Repair' formula so we can tackle telomere shortening from multiple angles.

But even slowing down the attrition, it cannot be stopped altogether (yet) - so what happens when telomeres are beyond 'critically short'?  When telomeres get too short the cell can no longer divide and the cell dies.  Sometimes it self-destructs (which is preferable, actually) and other times it hangs around unable to function properly and aptly nicknamed a 'zombie cell'. 

New research into senolytic cells teaches us some alarming facts about the impact of these zombie cells.  Not only can they get in the way of normal processes but they can also encourage healthy cells to malfunction too, as if recruiting an army of zombies.  Sadly, even a small fraction of zombie cells can hinder healing, immunity and health.  That's why 'Eliminate', our senolytic therapy is designed to clear these senescent cells as quickly as possible, to avoid the damage they can inflict.

At One Truth 818 we are the telomere experts and we are proud to be able to share this cutting edge research with you and tell the whole telomere story.  The long and the short of it!

Introducing Dr Steven Gabriel

Dr. Steven Gabriel, MD is a board-certified physician, who completed his residency in Emergency Medicine at UCLA Medical Center.

He completed his internship at the University of Hawaii, and is fellowship trained in Anti-Aging and Regenerative Medicine. He attended medical school at SUNY, Downstate medical center in New York, and completed his undergraduate work in microbiology and molecular genetics with a specialization in developmental disabilities at UCLA. While working as an Emergency Department physician, Dr. Gabriel became passionate about disease processes and aging. Because of this passion, he went on to complete a fellowship in Anti-Aging and Regenerative Medicine. He looks at aging as a disease process that we can stop rather than the inevitable course of life. 

Dr. Gabriel’s focus is in creating your optimal biologic outcome at the cellular level. His passion is in finding the absolute best superfoods, ways to eat, exercise programs, and proteins that work to make changes at the DNA and cellular level to create the youngest version of you. He has had the privilege of working with athletes and captains of industry to find the best solutions in reversing the aging process.

He has done further training in IV nutrition, genetics, skin and hair health, stem cells, and cellular rejuvenation.

Dr Gabriel is excited to be part of the One Truth 818 team. Our collaboration has resulted in our new Scientific Supplements range to introduce solutions to combat ageing and follow Dr Gabriel’s philosophy on living life to it’s most fulfilling.

CARNOSINE - slows telomere shortening by reducing oxidation of our telomeres, and delays cells from becoming senescent (asleep) Aging can be reversed at the cellular level, i.e telomere length and also at the systems level. Think of it in terms of a common cold, even though we can’t cure a cold we can do much to eleviate the systems, aging is much the same and Carnosine tackles many of the (symptoms) of aging. “If you take old human cells that are near senecense and place them in a bath of carnosine they become young again”. • Improves athletic performance • Helps with mood • People with cataracts see improvements in vision • Skin Improves and wound healing is accelerated

CURCUMIN-a powerful anti-inflammatory that helps prevent telomere shortening and also activates telomerase.

SILYBIN-the active ingredient in Milk Thistle increases the master anti-oxidant in our body, Glutathione, by around 30%. This protects our telomeres, and slows shortening while also improving liver health.

GLUTATHIONE-This is the master anti-Oxidant of all cells. Studies show that there is a direct relationship between glutathione levels and Telomerase activity.

CYCLOASTREGENOL-has been found in multiple studies to stimulate telomerase activity, and lengthen telomeres.

VITAMIN D3-Increases Telomerase activity and improves telomere maintenance. It also helps prevent cell death, and slows obesity-induced cellular aging.

PTEROSTILBENE- is a potent anti-oxidant, and is a more bioavailable type of Resveratrol. It is shown to cause apoptosis (programmed cell death) in mutated, and aged cells that would otherwise go on to cause aging.

QUERCETIN-this known senolytic is an antioxidant and has a powerful role in in causing apoptosis (programmed cell death) and in causing cells to go to sleep that are no longer functioning correctly. There are multiple studies looking at Quercetin and it’s effects on diseases related to aging.

ZINC-plays a powerful role working with Quercetin. Quercetin uses Zinc to carry out it’s role as a senolytic.

EGCG (Epigallocatechin)-the most powerful polyphenol in green tea, and is what is responsible for Green Tea’s anti aging effects. EGCG has a powerful role in regulating “sick cells”-it has senolytic effects causing cells that are aged or damaged to stop functioning and therefore prevent aging and disease.

Steps that have powerful effects on our cells telomeres are:

1. Eat a low inflammatory diet. The diet should consist of lots of fruits and vegetables and low amounts of animal protein including meat and dairy.

2. Do cardiovascular exercise for at least 30 minutes each day. Studies show that cardiovascular exercise helps our telomeres maintain length.

3. Take supplements that support our telomeres and improve getting rid of “bad cells’-like REPAIR and ELIMINATE.

4. Lower stress through meditation, yoga, or spending time doing things with those you love. Ultimately, this is what life’s all about and your cells know it. Lack of stress helps prevent telomeres from shortening.

Hear it for yourself

We have many stories from our customers...

"One Truth 818 has been so impressive. No flare-ups, no sensitivity. In fact One Truth has calmed and strengthened my skin in a way I have never experienced before."


Scientific Supplement Core Duo



  • How quickly will I see results?

    Most people notice a result within the first 2 weeks, if following suggested protocols of use. We suggest taking a ‘before’ shot so the consumer can really compare the difference. The results can be ‘subtle’ compared to botox or fillers for example, but a photo will demonstrate the improvements to fine lines and wrinkles, increased elasticity, decreased sensitivity, diminished hyperpigmentation and quality of pores.

  • How long will the products last?

    50ml units lasts approximately 8-10 weeks. That is, using the Serum twice daily and the Atomiser 4 times daily.

  • Are One Truth 818 products safe to use on sensitive skin?

    Yes. In fact the hydrating properties and the decrease in transepidermal water loss can help to strengthen skin and reduce sensitivity. TAM818 has been shown to rebuild capillaries and anecdotal evidence shows significant improvements on Rosacea inflicted skin.

  • What independent efficacy testing has been performed on TAM-818?

    In a 30-day time period TAM818 has been scientifically proven to:• Improve Skin Firmness by an average of 20.33%• Increase Skin Elasticity by 8.33%.• Improve Skin Smoothness and texture by 12.53% on the forehead and 9.63% in the eye area.• Decrease Forehead wrinkles by 14.04% and crows feet wrinkles by 11.07%.

  • Can I continue with all my other regular beauty treatments?

    Yes, please do! Except we recommend against the use of very high grade, surface damaging, exfoliation techniques and treatments which speed up the natural rate of cell division, thus causing increased telomere shortening and ultimately speeding up the rate of which your skin is ageing.

  • What kind of fragrance is used in One Truth 818 products?

    We only use natural, ecocertified ‘fragrance’ in our products

  • Does One Truth 818 contain parabens?

    One Truth 818 products do not contain parabens.

  • Where are One Truth 818 products manufactured?

    One Truth 818 is made in a GMP facility in New Zealand by Chase Life Extension Foundation Ltd who hold the license to use TAM-818 in a skincare product. Sierra Sciences are based in Reno, Nevada, USA